Sinead D. Cuffe: search on Z-Library

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1

Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer

Reck, Martin, Rodríguez-Abreu, Delvys, Robinson, Andrew G., Hui, Rina, Csőszi, Tibor, Fülöp, Andrea, Gottfried, Maya, Peled, Nir, Tafreshi, Ali, Cuffe, Sinead, O’Brien, Mary, Rao, Suman, Hotta, Katsuy

Journal:

New England Journal of Medicine

Year:

2016

Language:

english

File:

PDF, 252 KB

english, 2016

2

When your Best is not Good Enough

Anne M. Horgan, Sinead D. Cuffe, Jennifer J. Knox

Journal:

Journal of Cancer Education

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

3

Updated Analysis of KEYNOTE-024: Pembrolizumab Versus Platinum-Based Chemotherapy for Advanced Non–Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score of 50% or Greater

Reck, Martin, Rodríguez-Abreu, Delvys, Robinson, Andrew G., Hui, Rina, Csőszi, Tibor, Fülöp, Andrea, Gottfried, Maya, Peled, Nir, Tafreshi, Ali, Cuffe, Sinead, O’Brien, Mary, Rao, Suman, Hotta, Katsuy

Journal:

Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 785 KB

english, 2019

4

Health-related quality-of-life results for pembrolizumab versus chemotherapy in advanced, PD-L1-positive NSCLC (KEYNOTE-024): a multicentre, international, randomised, open-label phase 3 trial

Brahmer, Julie R, Rodríguez-Abreu, Delvys, Robinson, Andrew G, Hui, Rina, Csőszi, Tibor, Fülöp, Andrea, Gottfried, Maya, Peled, Nir, Tafreshi, Ali, Cuffe, Sinead, O'Brien, Mary, Rao, Suman, Hotta, Kat

Journal:

The Lancet Oncology

Year:

2017

Language:

english

File:

PDF, 442 KB

english, 2017

5

Cancer survivors' experience of OptiMal, a 6-week, occupation-based, self-management intervention

Boland, Lauren, Bennett, Kathleen, Cuffe, Sinead, Gleeson, Noreen, Grant, Cliona, Kennedy, John, Connolly, Deirdre

Journal:

The British Journal of Occupational Therapy

Year:

2018

Language:

english

File:

PDF, 470 KB

english, 2018

6

Cisplatin and gemcitabine in the management of metastatic penile cancer

Derek G. Power, David J. Galvin, Sinead Cuffe, Gerald P. McVey, Paul J. Mulholland, Cormac Farrelly, David W. Delaney, Kenneth J. O'Byrne

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

2009

Language:

english

File:

PDF, 907 KB

english, 2009

7

High Coexpression of Both EGFR and IGF1R Correlates With Poor Patient Prognosis in Resected Non–Small-Cell Lung Cancer

Gately, Kathy, Forde, Lydia, Cuffe, Sinead, Cummins, Robert, Kay, Elaine W., Feuerhake, Friedrich, O'Byrne, Kenneth J.

Journal:

Clinical Lung Cancer

Year:

2014

Language:

english

File:

PDF, 888 KB

english, 2014

8

The role of DNA repair pathways in cisplatin resistant lung cancer

O’Grady, Shane, Finn, Stephen P., Cuffe, Sinead, Richard, Derek J., O’Byrne, Kenneth J., Barr, Martin P.

Journal:

Cancer Treatment Reviews

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

9

The emerging role of microRNAs in resistance to lung cancer treatments

MacDonagh, Lauren, Gray, Steven G., Finn, Stephen P., Cuffe, Sinead, O’Byrne, Kenneth J., Barr, Martin P.

Journal:

Cancer Treatment Reviews

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

10

Strategic targeting of the PI3K–NFκB axis in cisplatin-resistant NSCLC

Heavey, Susan, Godwin, Peter, Baird, Anne-Marie, Barr, Martin P, Umezawa, Kazuo, Cuffe, Sinéad, Finn, Stephen P, O’Byrne, Kenneth J, Gately, Kathy

Journal:

Cancer Biology & Therapy

Year:

2014

Language:

english

File:

PDF, 9.32 MB

english, 2014

11

Cancer patients acceptance, understanding, and willingness-to-pay for pharmacogenomic testing

Cuffe, Sinead, Hon, Henrique, Qiu, Xin, Tobros, Kimberly, Wong, Chung-Kwun Amy, De Souza, Bradley, McFarlane, Graham, Masroor, Sohaib, Azad, Abul K., Hasani, Ekta, Rozanec, Natalie, Leighl, Natasha, A

Journal:

Pharmacogenetics and Genomics

Year:

2014

Language:

english

File:

PDF, 414 KB

english, 2014

12

Targeting the Phosphatidylinosital 3-Kinase, Akt, and Mammalian Target of Rapamycin Pathway in Non-small Cell Lung Cancer

Cuffe, Sinead, Leighl, Natasha B.

Journal:

Journal of Thoracic Oncology

Year:

2011

Language:

english

File:

PDF, 2.34 MB

english, 2011

13

Non-coding RNA repertoires in malignant pleural mesothelioma

Quinn, Leah, Finn, Stephen P., Cuffe, Sinead, Gray, Steven G.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.63 MB

english, 2015

14

Cancer stem cells in drug resistant lung cancer: Targeting cell surface markers and signaling pathways

Leon, Gemma, MacDonagh, Lauren, Finn, Stephen P., Cuffe, Sinead, Barr, Martin P.

Journal:

Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

15

Lung cancer stem cells: The root of resistance

MacDonagh, Lauren, Gray, Steven G., Breen, Eamon, Cuffe, Sinead, Finn, Stephen P., O'Byrne, Kenneth J., Barr, Martin P.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

16

KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma

Cregan, Sian, McDonagh, Lauran, Gao, Yun, Barr, Martin, O'Byrne, Kenneth, Finn, Stephen, Cuffe, Sinead, Gray, Steven

Journal:

International Journal of Oncology

Year:

2016

Language:

english

File:

PDF, 689 KB

english, 2016

17

Characteristics and Outcomes of Small Cell Lung Cancer Patients Diagnosed During Two Lung Cancer Computed Tomographic Screening Programs in Heavy Smokers

Cuffe, Sinead, Moua, Teng, Summerfield, Ruth, Roberts, Heidi, Jett, James, Shepherd, Frances A.

Journal:

Journal of Thoracic Oncology

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

18

A Pooled Exploratory Analysis of the Effect of Tumor Size and KRAS Mutations on Survival Benefit From Adjuvant Platinum-Based Chemotherapy in Node-Negative Non–Small Cell Lung Cancer

Cuffe, Sinead, Bourredjem, Abderrahmane, Graziano, Stephen, Pignon, Jean-Pierre, Domerg, Caroline, Ezzalfani, Monia, Seymour, Lesley, Strevel, Elizabeth, Burkes, Ronald, Capelletti, Marzia, Jänne, Pas

Journal:

Journal of Thoracic Oncology

Year:

2012

Language:

english

File:

PDF, 1.72 MB

english, 2012

19

Targeting the fibroblast growth factor receptor family in cancer

Hallinan, Niamh, Finn, Stephen, Cuffe, Sinead, Rafee, Shereen, O’Byrne, Kenneth, Gately, Kathy

Journal:

Cancer Treatment Reviews

Year:

2016

Language:

english

File:

PDF, 935 KB

english, 2016

20

ABCC2 polymorphisms and survival in the Princess Margaret cohort study and the NCIC clinical trials group BR.24 trial of platinum-treated advanced stage non-small cell lung cancer patients

Cuffe, Sinead, Azad, Abul Kalam, Qiu, Xiaoping, Qiu, Xin, Brhane, Yonathan, Kuang, Qin, Marsh, Sharon, Savas, Sevtap, Chen, Zhuo, Cheng, Dangxiao, Leighl, Natasha B., Goss, Glenwood, Laurie, Scott A.,

Journal:

Cancer Epidemiology

Year:

2016

Language:

english

File:

PDF, 554 KB

english, 2016

21

The IL-17-Th1/Th17 pathway: An attractive target for lung cancer therapy?

Joerger, Markus, Finn, Stephen P., Cuffe, Sinead, Byrne, Annette T., Gray, Steven G.

Journal:

Expert Opinion on Therapeutic Targets

Year:

2016

Language:

english

File:

PDF, 912 KB

english, 2016

22

PD-L1 as a Companion Biomarker for Immune Checkpoint Inhibitors in NSCLC: Should RNA ISH (RISH) Be Considered?

Gray, Steven G., Cuffe, Sinéad, Finn, Stephen P.

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 482 KB

english, 2016

23

P3.02c-010 Resistance Mechanisms to PI3K-mTOR Inhibition in NSCLC

Moore, Gillian, Heavey, Susan, O’Byrne, Kenneth, Finn, Stephen, Cuffe, Sinead, O'Neill, Michael, Gately, Kathy

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 146 KB

english, 2017

24

Kdm6a and Kdm6b: Altered expression in malignant pleural mesothelioma

Cregan, Sian, Breslin, Maeve, Roche, Gerard, Wennstedt, Sigrid, MacDonagh, Lauren, Albadri, Cinaria, Gao, Yun, O'Byrne, Kenneth, Cuffe, Sinead, Finn, Stephen, Gray, Steven

Journal:

International Journal of Oncology

Year:

2017

Language:

english

File:

PDF, 681 KB

english, 2017

25

P1.02-021 Review of Clinical Outcomes Attributable to Next Generation Sequencing Based Broad Mutation Panel Testing in Lung Adenocarcinoma

O'Brien, Cathal, Brosnan, Kathleen, Cuffe, Sinead, Finn, Stephen

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 175 KB

english, 2017

26

PL04a.01: Health-Related Quality of Life for Pembrolizumab vs Chemotherapy in Advanced NSCLC with PD-L1 TPS ≥50%: Data from KEYNOTE-024

Brahmer, Julie R., Rodríguez-Abreu, Delvys, Robinson, Andrew G., Hui, Rina, Csőszi, Tibor, Fülöp, Andrea, Gottfried, Maya, Peled, Nir, Tafreshi, Ali, Cuffe, Sinead, O’Brien, Mary, Rao, Suman, Hotta, K

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 153 KB

english, 2017

27

P1.05-021 circRNAs: Potential Novel Biomarkers for the Early Detection of Lung Cancer

Lin, Ruby, Reid, Glen, Mutti, Luciano, Ryan, Anthony, Nicholson, Siobhan, Leonard, Niamh, Young, Vincent, Ryan, Ronan, Finn, Stephen, Cuffe, Sinead, Gray, Steven

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 203 KB

english, 2017

28

P2.01-066 PD-L1 Tumor Expression and Its Effect on Overall Survival among Patients with Resected Non-Small Cell Lung Cancer (NSCLC)

Sui, Jane, Teo, Min Yuen, Rafee, Shereen, Fadden, Julie Mc, Gately, Kathy, Barr, Martin, Gray, Steven, Cuffe, Sinead, Finn, Stephen

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 129 KB

english, 2017

29

P2.03a-064 Inhibition and Exploitation of Aldehyde Dehydrogenase 1 as a Cancer Stem Cell Marker to Overcome Cisplatin Resistant NSCLC

Donagh, Lauren Mac, Gray, Steven, Finn, Stephen, Cuffe, Sinead, Gallagher, Michael, O’Byrne, Kenneth, Barr, Martin

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 127 KB

english, 2017

30

P2.03a-063 Small Molecule Cancer Stemness Inhibitor, BBI608, Restores Cisplatin Sensitivity in Resistant NSCLC

Donagh, Lauren Mac, Gray, Steven, Cuffe, Sinead, Finn, Stephen, O’Byrne, Kenneth, Barr, Martin

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 169 KB

english, 2017

31

P2.01-031 CCL Chemokines May Play an Important Role in Cisplatin Resistance

Ryan, Sarah-Louise, Godwin, Peter, Heavey, Susan, Umezawa, Kazuo, Barr, Martin, Gray, Steven, Stanfill, Bryan, Davies, Anthony, Cuffe, Sinead, Finn, Stephen, Richard, Derek, Gately, Kathy, O’Byrne, Ke

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 207 KB

english, 2017

32

P2.03a-062 Characterization and Targeting of the DNA Repair Gene, XRCC6BP1, in Cisplatin Resistant NSCLC

Barr, Martin, Singh, Saravjeet, Foley, Emma, He, Yuexi, Young, Vincent, Ryan, Ronan, Nicholson, Siobhan, Leonard, Niamh, Cuffe, Sinead, O’Byrne, Kenneth, Finn, Stephen

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 171 KB

english, 2017

33

P3.02c-030 Use of a 200-Mg Fixed Dose of Pembrolizumab for the Treatment of Advanced Non–Small Cell Lung Cancer (NSCLC)

Garon, Edward, Reck, Martin, Rodríguez-Abreu, Delvys, Robinson, Andrew, Hui, Rina, Tibor, Csőszi, Fülöp, Andrea, Gottfried, Maya, Peled, Nir, Tafreshi, Ali, Cuffe, Sinead, O'Brien, Mary, Rao, Suman, H

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 270 KB

english, 2017

34

P3.01-042 Lung Cancer Cells Can Stimulate Functional and Genotypic Modifications in Normal Bronchial Epithelial Cells

Baird, Anne-Marie, Barr, Martin, Ryan, Sarah-Louise, Gray, Steven, Davies, Anthony, Cuffe, Sinead, Finn, Stephen, Richard, Derek, O’Byrne, Kenneth

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 129 KB

english, 2017

35

P1.02-065 Elucidating the Role of PIM Kinase and Its Therapeutic Potential in NSCLC

Moore, Gillian, Heavey, Susan, Lightner, Clara, Brady, Lauren, O’Byrne, Kenneth, Finn, Stephen, Cuffe, Sinead, O'Neill, Michael, Gately, Kathy

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 178 KB

english, 2017

36

MA02.02 A Novel 5-miR Signature Shows Promise as a Diagnostic Tool and as a Predictor of Cisplatin Response in NSCLC

Donagh, Lauren Mac, Gray, Steven, Cuffe, Sinead, Finn, Stephen, Fitzgerald, Niamh, Young, Vincent, Ryan, Ronan, Nicholson, Siobhan, Leonard, Niamh, O’Byrne, Kenneth, Barr, Martin

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 171 KB

english, 2017

37

Outcomes for Esophageal Squamous Cell Carcinoma Treated with Curative Intent in a Western Cohort: Should Multimodal Therapy Be the Gold Standard?

Sheil, Fiachra, Donohoe, Claire L., King, Sinéad, O’Toole, Dermot, Cunningham, Moya, Cuffe, Sinéad, Ravi, Narayanasamy, Reynolds, John V.

Journal:

World Journal of Surgery

Year:

2017

Language:

english

File:

PDF, 594 KB

english, 2017

38

Development and characterisation of a panel of phosphatidylinositide 3-kinase – mammalian target of rapamycin inhibitor resistant lung cancer cell lines

Heavey, Susan, Dowling, Paul, Moore, Gillian, Barr, Martin P., Kelly, Niamh, Maher, Stephen G., Cuffe, Sinead, Finn, Stephen P., O’Byrne, Kenneth J., Gately, Kathy

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.09 MB

english, 2018

39

BBI608 inhibits cancer stemness and reverses cisplatin resistance in NSCLC

MacDonagh, Lauren, Gray, Steven G., Breen, Eamon, Cuffe, Sinead, Finn, Stephen P., O'Byrne, Kenneth J., Barr, Martin P.

Journal:

Year:

2018

Language:

english

File:

PDF, 992 KB

english, 2018

40

Brief report on the detection of the EGFR-T790M mutation in exhaled breath condensate from lung cancer patients

Smyth, Robert J., Toomey, Sinead M., Sartori, Alexander, Hanrahan, Emer O., Cuffe, Sinead D., Breathnach, Oscar S., Morgan, Ross K., Hennessy, Bryan T.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 697 KB

english, 2018

41

Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells

Heery, Richard, Finn, Stephen, Cuffe, Sinead, Gray, Steven

Journal:

Year:

2017

Language:

english

File:

PDF, 921 KB

english, 2017

42

Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples

O’Brien, Odharnaith, Wright, Mark, O’Brien, Cathal, Geoghegan, Orla, Leonard, Niamh, Nicholson, Siobhan, Cuffe, Sinéad, Fabre, Aurelie, Jochum, Wolfram, Joerger, Markus, Gray, Steven, Finn, Stephen

Journal:

Year:

2019

Language:

english

File:

PDF, 1.94 MB

english, 2019

43

Updated Analysis of KEYNOTE-024: Pembrolizumab Versus Platinum-Based Chemotherapy for Advanced Non–Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score of 50% or Greater

Reck, Martin, Rodríguez-Abreu, Delvys, Robinson, Andrew G., Hui, Rina, Csőszi, Tibor, Fülöp, Andrea, Gottfried, Maya, Peled, Nir, Tafreshi, Ali, Cuffe, Sinead, O’Brien, Mary, Rao, Suman, Hotta, Katsuy

Journal:

Journal of Clinical Oncology

Year:

2019

File:

PDF, 785 KB

2019

44

In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC

Heavey, Susan, Cuffe, Sinead, Finn, Stephen, Young, Vincent, Ryan, Ronan, Nicholson, Siobhan, Leonard, Niamh, McVeigh, Niall, Barr, Martin, O’Byrne, Kenneth, Gately, Kathy

Journal:

Year:

2016

File:

PDF, 6.25 MB

2016

45

In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC

Heavey, Susan, Cuffe, Sinead, Finn, Stephen, Young, Vincent, Ryan, Ronan, Nicholson, Siobhan, Leonard, Niamh, McVeigh, Niall, Barr, Martin, O’Byrne, Kenneth, Gately, Kathy

Journal:

Year:

2016

Language:

english

File:

PDF, 6.25 MB

english, 2016

46

Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer

Malone, Tom, Schӓfer, Lea, Simon, Nathalie, Heavey, Susan, Cuffe, Sinead, Finn, Stephen, Moore, Gillian, Gately, Kathy

Journal:

Pharmacology & Therapeutics

Year:

2019

File:

PDF, 1.02 MB

2019

47

Modern oncological and operative outcomes in esophageal cancer: the St. Jamesâs hospital experience

Donlon, Noel E., Ravi, Narayanasamy, King, Sinead, Cunninhgam, Moya, Cuffe, Sinead, Lowery, Maeve, Wall, Carmel, Hughes, Niall, Muldoon, Cian, Ryan, Ciara, Moore, Jenny, OâFarrell, Catherine, Gorry,

Journal:

Irish Journal of Medical Science (1922-1925)

Year:

2020

File:

PDF, 363 KB

2020